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Oxidants, antioxidants, and the degenerative diseases of aging.

Metabolism, like other aspects of life, involves tradeoffs. Oxidant by-products of normal metabolism cause extensive damage to DNA, protein, and lipid. We argue that this damage (the same as that produced by radiation) is a major contributor to aging and to degenerative diseases of aging such as can...

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Detalhes bibliográficos
Main Authors: Ames, B N, Shigenaga, M K, Hagen, T M
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC47258/
https://ncbi.nlm.nih.gov/pubmed/8367443
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