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Conserved Patterns of Microbial Immune Escape: Pathogenic Microbes of Diverse Origin Target the Human Terminal Complement Inhibitor Vitronectin via a Single Common Motif

Pathogenicity of many microbes relies on their capacity to resist innate immunity, and to survive and persist in an immunocompetent human host microbes have developed highly efficient and sophisticated complement evasion strategies. Here we show that different human pathogens including Gram-negative...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Hallström, Teresia, Singh, Birendra, Kraiczy, Peter, Hammerschmidt, Sven, Skerka, Christine, Zipfel, Peter F., Riesbeck, Kristian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725753/
https://ncbi.nlm.nih.gov/pubmed/26808444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147709
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