Effects of probenecid and cimetidine on the pharmacokinetics of nemonoxacin in healthy Chinese volunteers

PURPOSE: To investigate the effects of probenecid and cimetidine on the pharmacokinetics of nemonoxacin in humans. METHODS: Two independent, open-label, randomized, crossover studies were conducted in 24 (12 per study) healthy Chinese volunteers. In Study 1, each volunteer received a single oral dos...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zhang, Yi-fan, Dai, Xiao-jian, Yang, Yong, Chen, Xiao-yan, Wang, Ting, Tang, Yun-biao, Tsai, Cheng-yuan, Chang, Li-wen, Chang, Yu-ting, Zhong, Da-fang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725632/
https://ncbi.nlm.nih.gov/pubmed/26855561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S95934
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