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Acute Changes in Striatal Microstructure Predict the Development of Interferon-Alpha Induced Fatigue

BACKGROUND: Interferon-alpha (IFN-α) is a key mediator of antiviral immune responses used clinically for hepatitis C treatment. Though effective, IFN-α induces marked behavioral changes that, when severe, can appear indistinguishable from major depression. Curiously, fatigue and motivational impairm...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Dowell, Nicholas G., Cooper, Ella A., Tibble, Jeremy, Voon, Valerie, Critchley, Hugo D., Cercignani, Mara, Harrison, Neil A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725575/
https://ncbi.nlm.nih.gov/pubmed/26169252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.05.015
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