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Micronucleus formation causes perpetual unilateral chromosome inheritance in mouse embryos
Chromosome segregation defects in cancer cells lead to encapsulation of chromosomes in micronuclei (MN), small nucleus-like structures within which dangerous DNA rearrangements termed chromothripsis can occur. Here we uncover a strikingly different consequence of MN formation in preimplantation deve...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4725495/ https://ncbi.nlm.nih.gov/pubmed/26729872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517628112 |
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