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Lamin A/C deficiency reduces circulating tumor cell resistance to fluid shear stress

Metastasis contributes to over 90% of cancer-related deaths and is initiated when cancer cells detach from the primary tumor, invade the basement membrane, and enter the circulation as circulating tumor cells (CTCs). While metastasis is viewed as an inefficient process with most CTCs dying within th...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Mitchell, Michael J., Denais, Celine, Chan, Maxine F., Wang, Zhexiao, Lammerding, Jan, King, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725441/
https://ncbi.nlm.nih.gov/pubmed/26447202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00050.2015
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