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A novel gain of function mutant in C-kit gene and its tumorigenesis in nude mice
AIM: To transfect mutant C-kit cDNA at codon 579 into human embryonic kidney cell line to observe its role in the pathogenesis of gastrointestinal stromal tumor (GIST). METHODS: Eukaryotic expression vectors of pcDNA3-Kit-NW and pcDNA3-Kit-W were constructed. Then pcDNA3-Kit-NW and pcDNA3-Kit-W plas...
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| Publicado no: | World J Gastroenterol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Inc
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4725073/ https://ncbi.nlm.nih.gov/pubmed/16437655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i45.7104 |
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