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Analysis of the Protein Kinase A-Regulated Proteome of Cryptococcus neoformans Identifies a Role for the Ubiquitin-Proteasome Pathway in Capsule Formation

The opportunistic fungal pathogen Cryptococcus neoformans causes life-threatening meningitis in immunocompromised individuals. The expression of virulence factors, including capsule and melanin, is in part regulated by the cyclic-AMP/protein kinase A (cAMP/PKA) signal transduction pathway. In this s...

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Vydáno v:mBio
Hlavní autoři: Geddes, J. M. H., Caza, M., Croll, D., Stoynov, N., Foster, L. J., Kronstad, J. W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725006/
https://ncbi.nlm.nih.gov/pubmed/26758180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01862-15
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