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MicroRNA‐27b suppresses tumor progression by regulating ARFGEF1 and focal adhesion signaling

The non‐receptor tyrosine kinase c‐Src is frequently activated during progression of colon cancers. In this study, we found that among the c‐Src‐regulated microRNAs (miRNAs), miR‐27b is also repressed by activation of K‐Ras/H‐Ras. Inhibitor studies suggested that the phosphatidylinositol 3‐kinase pa...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Matsuyama, Rei, Okuzaki, Daisuke, Okada, Masato, Oneyama, Chitose
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724816/
https://ncbi.nlm.nih.gov/pubmed/26473412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12834
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