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Complement component 3 (C3) is regulated by TWIST1 and mediates epithelial-mesenchymal transition (EMT)
We have previously shown that complement component 3 (C3) is secreted by malignant epithelial cells. To understand the mechanism of upregulation of C3 expression in tumor cells we studied the C3 promoter; and identified that TWIST1 binds to the C3 promoter and enhances its expression. Because TWIST1...
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| Udgivet i: | J Immunol |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4724537/ https://ncbi.nlm.nih.gov/pubmed/26718342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501886 |
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