Identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activities

Treating bacterial infections can be difficult due to innate or acquired resistance mechanisms, and the formation of biofilms. Cyclic lipopeptides derived from fusaricidin/LI-F natural products represent particularly attractive candidates for the development of new antibacterial and antibiofilm agen...

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Publicat a:Eur J Med Chem
Autors principals: Bionda, Nina, Fleeman, Renee M., de la Fuente-Núñez, César, Rodriguez, Maria C., Reffuveille, Fany, Shaw, Lindsey N., Pastar, Irena, Davis, Stephen C., Hancock, Robert E. W., Cudic, Predrag
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724249/
https://ncbi.nlm.nih.gov/pubmed/26703794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.11.032
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