Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness.

The low-affinity p75 neurotrophin receptor is believed to participate with the Trk receptor tyrosine kinase in the formation of high-affinity binding sites for nerve growth factor (NGF). To investigate the functional significance of the two NGF receptors, a truncated p75 receptor was stably expresse...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Benedetti, M, Levi, A, Chao, M V
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47242/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8356095/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7859
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