Polymer models for interphase chromosomes.

The overall geometry of chromosomes in mammalian cells during interphase is analyzed. On scales larger than approximately 10(5) bp, a chromosome is modeled as a Gaussian polymer subjected to additional forces that confine it to a subvolume of the cell nucleus. An appropriate partial differential equ...

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Main Authors: Hahnfeldt, P, Hearst, J E, Brenner, D J, Sachs, R K, Hlatky, L R
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC47241/
https://ncbi.nlm.nih.gov/pubmed/8356094
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