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Reduced metallothionein expression induced by Zinc deficiency results in apoptosis in hepatic stellate cell line LX-2

The present study is to investigate the molecular mechanism by which Zinc (Zn) deficiency induces apoptosis in hepatic stellate cells. LX-2 cells were incubated with N,N,N’,N’-tetrakis(2-pyridylmethyl)ethane-1,2-diamine (TPEN; 5 μM, 10 μM and 25 μM) for 24 h. MTT assay was used to test the prolifera...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Kang, Min, Zhao, Lei, Ren, Meiping, Deng, Mingming, Li, Changping
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723824/
https://ncbi.nlm.nih.gov/pubmed/26884979
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