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Overexpression of long non-coding RNA PVT1 in ovarian cancer cells promotes cisplatin resistance by regulating apoptotic pathways

Ovarian cancer is the most lethal gynecologic malignancy. Cisplatin is a very effective cancer chemotherapy drug, but cisplatin resistance is a crucial problem of therapy failure. Overexpression of PVT1 has been demonstrated in ovarian cancer. The mRNA level of PVT1 in ovarian cancer tissues of cisp...

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Bibliografiske detaljer
Udgivet i:Int J Clin Exp Med
Main Authors: Liu, Enling, Liu, Zheng, Zhou, Yuxiu, Mi, Ruoran, Wang, Dehua
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723819/
https://ncbi.nlm.nih.gov/pubmed/26884974
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