Diosgenin attenuates hepatic stellate cell activation through transforming growth factor-β/Smad signaling pathway

Activation of hepatic stellate cells (HSC) plays a pivotal role in the development of hepatic fibrosis. Transforming growth factor-β1 (TGF-β1) is considered to be the main stimuli factor responsible for the activation of HSC. Diosgenin is a steroidal saponin found in several plants including Solanum...

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Bibliografische gegevens
Gepubliceerd in:Int J Clin Exp Med
Hoofdauteurs: Xie, Wei-Lin, Jiang, Rong, Shen, Xiao-Lu, Chen, Zhi-Yu, Deng, Xiao-Ming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2015
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723792/
https://ncbi.nlm.nih.gov/pubmed/26884947
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