Alemtuzumab long-term immunologic effect: Treg suppressor function increases up to 24 months

OBJECTIVE: To analyze changes in T-helper (Th) subsets, T-regulatory (Treg) cell percentages and function, and mRNA levels of immunologically relevant molecules during a 24-month follow-up after alemtuzumab treatment in patients with relapsing-remitting multiple sclerosis (RRMS). METHODS: Multicente...

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Publicado en:Neurol Neuroimmunol Neuroinflamm
Autores principales: De Mercanti, Stefania, Rolla, Simona, Cucci, Angele, Bardina, Valentina, Cocco, Eleonora, Vladic, Anton, Soldo-Butkovic, Silva, Habek, Mario, Adamec, Ivan, Horakova, Dana, Annovazzi, Pietro, Novelli, Francesco, Durelli, Luca, Clerico, Marinella
Formato: Artigo
Lenguaje:Inglês
Publicado: Lippincott Williams & Wilkins 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723135/
https://ncbi.nlm.nih.gov/pubmed/26819963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000194
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