A local renal renin–angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats

The mechanism of activation of local renal renin–angiotensin system (RAS) has not been clarified in diabetes mellitus (DM). We hypothesized that the local renal RAS will be activated via increased glomerular filtration and tubular uptake of prorenin and angiotensinogen in diabetic kidney with microa...

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Detaylı Bibliyografya
Yayımlandı:Diabetes Metab Syndr Obes
Asıl Yazarlar: Tojo, Akihiro, Kinugasa, Satoshi, Fujita, Toshiro, Wilcox, Christopher S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove Medical Press 2016
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723098/
https://ncbi.nlm.nih.gov/pubmed/26848273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S91245
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