PCSK9 Plasma Concentrations Are Independent of GFR and Do Not Predict Cardiovascular Events in Patients with Decreased GFR

BACKGROUND: Impaired renal function causes dyslipidemia that contributes to elevated cardiovascular risk in patients with chronic kidney disease (CKD). The proprotein convertase subtilisin/kexin type 9 (PCSK9) is a regulator of the LDL receptor and plasma cholesterol concentrations. Its relationship...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rogacev, Kyrill S., Heine, Gunnar H., Silbernagel, Günther, Kleber, Marcus E., Seiler, Sarah, Emrich, Insa, Lennartz, Simone, Werner, Christian, Zawada, Adam M., Fliser, Danilo, Böhm, Michael, März, Winfried, Scharnagl, Hubert, Laufs, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723078/
https://ncbi.nlm.nih.gov/pubmed/26799206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146920
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