PCSK9 Plasma Concentrations Are Independent of GFR and Do Not Predict Cardiovascular Events in Patients with Decreased GFR

BACKGROUND: Impaired renal function causes dyslipidemia that contributes to elevated cardiovascular risk in patients with chronic kidney disease (CKD). The proprotein convertase subtilisin/kexin type 9 (PCSK9) is a regulator of the LDL receptor and plasma cholesterol concentrations. Its relationship...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Rogacev, Kyrill S., Heine, Gunnar H., Silbernagel, Günther, Kleber, Marcus E., Seiler, Sarah, Emrich, Insa, Lennartz, Simone, Werner, Christian, Zawada, Adam M., Fliser, Danilo, Böhm, Michael, März, Winfried, Scharnagl, Hubert, Laufs, Ulrich
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723078/
https://ncbi.nlm.nih.gov/pubmed/26799206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146920
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