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The functions of TRPP2 in the vascular system
TRPP2 (polycystin-2, PC2 or PKD2), encoded by the PKD2 gene, is a non-selective cation channel with a large single channel conductance and high Ca(2+) permeability. In cell membrane, TRPP2, along with polycystin-1, TRPV4 and TRPC1, functions as a mechanotransduction channel. In the endoplasmic retic...
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| Udgivet i: | Acta Pharmacol Sin |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4722977/ https://ncbi.nlm.nih.gov/pubmed/26725733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.126 |
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