Eliciting cytotoxic T lymphocytes against human laryngeal cancer-derived antigens: evaluation of dendritic cells pulsed with a heat-treated tumor lysate and other antigen-loading strategies for dendritic-cell-based vaccination

BACKGROUND: Dendritic cells (DCs) have been used successfully in clinical pilot studies. However, tumor-specific immunity and clinical responses were only induced in certain cancer patients. It has been well documented that immunotherapy efficacy can be optimized for responses using antigen pulsing....

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Bibliographische Detailangaben
Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Wei, Fan-Qin, Sun, Wei, Wong, Thian-Sze, Gao, Wei, Wen, Yi-Hui, Wei, Jia-Wei, Wei, Yi, Wen, Wei-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722756/
https://ncbi.nlm.nih.gov/pubmed/26795730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0295-1
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