Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial

Whether initiation of antiretroviral therapy (ART) regimens aimed at achieving greater concentrations within gut associated lymphoid tissue (GALT) impacts the level of mucosal immune reconstitution, inflammatory markers and the viral reservoir remains unknown. We included 12 HIV- controls and 32 ART...

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Publicat a:PLoS Pathog
Autors principals: Serrano-Villar, Sergio, Sainz, Talia, Ma, Zhong-Min, Utay, Netanya S., Wook-Chun, Tae, Mann, Surinder, Kashuba, Angela D., Siewe, Basile, Albanese, Anthony, Troia-Cancio, Paolo, Sinclair, Elizabeth, Somasunderam, Anoma, Yotter, Tammy, Deeks, Steven G., Landay, Alan, Pollard, Richard B., Miller, Christopher J., Moreno, Santiago, Asmuth, David M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721954/
https://ncbi.nlm.nih.gov/pubmed/26795282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005381
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