Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome

Most West Nile virus (WNV) infections are asymptomatic, but some lead to neuroinvasive disease with symptoms ranging from disorientation to paralysis and death. Evidence from animal models suggests that neuroinvasive infections may arise as a consequence of impaired immune protection. However, other...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: James, Eddie A., Gates, Theresa J., LaFond, Rebecca E., Yamamoto, Shinobu, Ni, Chester, Mai, Duy, Gersuk, Vivian H., O’Brien, Kimberly, Nguyen, Quynh-Anh, Zeitner, Brad, Lanteri, Marion C., Norris, Philip J., Chaussabel, Damien, Malhotra, Uma, Kwok, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721872/
https://ncbi.nlm.nih.gov/pubmed/26795118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005375
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