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Epitopes for natural antibodies of human immunodeficiency virus (HIV)-negative (normal) and HIV-positive sera are coincident with two key functional sequences of HIV Tat protein.

We have previously shown that IgM antibodies that react with human immunodeficiency virus (HIV) Tat, a regulatory protein essential for viral replication, are present in sera of all normal, HIV-negative individuals and deficient in sera of HIV-positive individuals at progressively greater frequency...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Rodman, T C, To, S E, Hashish, H, Manchester, K
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47214/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7689227/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7719
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