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The importance of hypoxia and EPHOSS for collection and processing of stem and progenitor cells to understand true physiology/pathology of these cells ex-vivo
PURPOSE OF REVIEW: Hematopoietic stem (HSCs), and progenitor (HPCs) cells reside in a hypoxic (lowered oxygen (O(2)) tension) environment, in vivo. We review literature on growth of HSCs and HPCs under hypoxic and normoxic (ambient air) conditions with a focus on our recent work demonstrating the de...
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| Veröffentlicht in: | Curr Opin Hematol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4721218/ https://ncbi.nlm.nih.gov/pubmed/26049746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000144 |
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