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The N-terminal coiled-coil domain of beta is essential for gamma association: a model for G-protein beta gamma subunit interaction.

We have identified the N terminus of the beta subunit as an essential domain for G-protein beta gamma assembly. A C-terminal fragment, beta 1-(130-340), fails to bind gamma unless coexpressed with the complementary N-terminal fragment, beta 1-(1-129). Deletion of the N-terminal 33 residues of beta 1...

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Main Authors: Garritsen, A, van Galen, P J, Simonds, W F
格式: Artigo
語言:Inglês
出版: 1993
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC47211/
https://ncbi.nlm.nih.gov/pubmed/8356073
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