Integrative DNA methylome analysis of pan-cancer biomarkers in cancer discordant monozygotic twin-pairs

BACKGROUND: A key focus in cancer research is the discovery of biomarkers that accurately diagnose early lesions in non-invasive tissues. Several studies have identified malignancy-associated DNA methylation changes in blood, yet no general cancer biomarker has been identified to date. Here, we expl...

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發表在:Clin Epigenetics
Main Authors: Roos, Leonie, van Dongen, Jenny, Bell, Christopher G., Burri, Andrea, Deloukas, Panos, Boomsma, Dorret I., Spector, Tim D., Bell, Jordana T.
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721070/
https://ncbi.nlm.nih.gov/pubmed/26798410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0172-y
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