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The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development
Tumor necrosis factor receptor–associated factor 3 (TRAF3) is an adaptor protein that inhibits signaling by CD40 and by the receptor for B cell–activating factor (BAFF) and negatively regulates homeostatic B cell survival. Loss-of-function mutations in TRAF3 are associated with human B cell malignan...
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| 發表在: | Sci Signal |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4720969/ https://ncbi.nlm.nih.gov/pubmed/26329582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa5157 |
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