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The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells.

Three members of the Src family of protein tyrosine kinases Src, Fyn, and Yes associate with the activated platelet-derived growth factor (PDGF) receptor in vivo. This interaction requires the Src homology 2 (SH2) domain of the Src family member and causes activation of the intrinsic activity of the...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Twamley-Stein, G M, Pepperkok, R, Ansorge, W, Courtneidge, S A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47209/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8356071/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7696
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