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In Vitro Selectivity of an Acyclic Cucurbit[n]uril Molecular Container towards Neuromuscular Blocking Agents Relative to Commonly Used Drugs
An acyclic cucurbit[n]uril (CB[n]) based molecular container (2, a.k.a. Calabadion 2) binds to both amino-steroidal and benzylisoquinolinium type neuromuscular blocking agents (NMBAs) in vitro, and reverses the effect of these drugs in vivo displaying faster recovery times than placebo and the γ-cyc...
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| Gepubliceerd in: | Org Biomol Chem |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4720557/ https://ncbi.nlm.nih.gov/pubmed/26648135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob02356d |
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