Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes.

Eitemau Tebyg

• Substitution of cysteine 192 in a highly conserved Streptococcus pyogenes extracellular cysteine protease (interleukin 1beta convertase) alters proteolytic activity and ablates zymogen processing.
  gan: Musser, J M, et al.
  Cyhoeddwyd: (1996)
• Fibrinogen Cleavage by the Streptococcus pyogenes Extracellular Cysteine Protease and Generation of Antibodies That Inhibit Enzyme Proteolytic Activity
  gan: Matsuka, Yury V., et al.
  Cyhoeddwyd: (1999)
• Different forms of streptolysin O produced by Streptococcus pyogenes and by Escherichia coli expressing recombinant toxin: cleavage by streptococcal cysteine protease.
  gan: Pinkney, M, et al.
  Cyhoeddwyd: (1995)
• Activation of a 66-kilodalton human endothelial cell matrix metalloprotease by Streptococcus pyogenes extracellular cysteine protease.
  gan: Burns, E H, et al.
  Cyhoeddwyd: (1996)
• Extracellular Cysteine Protease Produced by Streptococcus pyogenes Participates in the Pathogenesis of Invasive Skin Infection and Dissemination in Mice
  gan: Lukomski, Slawomir, et al.
  Cyhoeddwyd: (1999)