Changes in Colonic Bile Acid Composition following Fecal Microbiota Transplantation Are Sufficient to Control Clostridium difficile Germination and Growth

Fecal microbiota transplantation (FMT) is a highly effective therapy for recurrent Clostridium difficile infection (R-CDI), but its mechanisms remain poorly understood. Emerging evidence suggests that gut bile acids have significant influence on the physiology of C. difficile, and therefore on patie...

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Udgivet i:PLoS One
Main Authors: Weingarden, Alexa R., Dosa, Peter I., DeWinter, Erin, Steer, Clifford J., Shaughnessy, Megan K., Johnson, James R., Khoruts, Alexander, Sadowsky, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720481/
https://ncbi.nlm.nih.gov/pubmed/26789728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147210
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