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Chronic Uridine Administration Induces Fatty Liver and Pre-Diabetic Conditions in Mice

Uridine is a pyrimidine nucleoside that exerts restorative functions in tissues under stress. Short-term co-administration of uridine with multiple unrelated drugs prevents drug-induced liver lipid accumulation. Uridine has the ability to modulate liver metabolism; however, the precise mechanism has...

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Vydáno v:PLoS One
Hlavní autoři: Urasaki, Yasuyo, Pizzorno, Giuseppe, Le, Thuc T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720477/
https://ncbi.nlm.nih.gov/pubmed/26789264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146994
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