Stat3 Signaling Promotes Survival And Maintenance Of Medullary Thymic Epithelial Cells

Medullary thymic epithelial cells (mTECs) are essential for establishing central tolerance by expressing a diverse array of self-peptides that delete autoreactive thymocytes and/or divert thymocytes into the regulatory T cell lineage. Activation of the NFκB signaling pathway in mTEC precursors is in...

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Bibliografski detalji
Izdano u:PLoS Genet
Glavni autori: Lomada, Dakshayani, Jain, Manju, Bolner, Michelle, Reeh, Kaitlin A. G., Kang, Rhea, Reddy, Madhava C., DiGiovanni, John, Richie, Ellen R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720390/
https://ncbi.nlm.nih.gov/pubmed/26789196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005777
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