Ceramide Production Mediates Aldosterone-Induced Human Umbilical Vein Endothelial Cell (HUVEC) Damages

Here, we studied the underlying mechanism of aldosterone (Aldo)-induced vascular endothelial cell damages by focusing on ceramide. We confirmed that Aldo (at nmol/L) inhibited human umbilical vein endothelial cells (HUVEC) survival, and induced considerable cell apoptosis. We propose that ceramide (...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhang, Yumei, Pan, Yu, Bian, Zhixiang, Chen, Peihua, Zhu, Shijian, Gu, Huiyi, Guo, Liping, Hu, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720365/
https://ncbi.nlm.nih.gov/pubmed/26788916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146944
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