A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein.

Initiation of translation of the RNA genomes of picornaviruses such as poliovirus and encephalomyocarditis virus is cap-independent and results from interaction of ribosomes with a segment of the 5' noncoding region of these mRNAs termed the internal ribosomal entry site. Genetic and biochemical stu...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hellen, C U, Witherell, G W, Schmid, M, Shin, S H, Pestova, T V, Gil, A, Wimmer, E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47198/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8395052/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7642
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