Early changes in blood-based joint tissue destruction biomarkers are predictive of response to tocilizumab in the LITHE study

BACKGROUND: Rheumatoid arthritis (RA) is characterized by gradual joint destruction. Tocilizumab (TCZ) significantly suppresses symptoms, however not all patients are protected from joint damage. We investigated whether early measurement of specific biomarkers could predict early joint protection re...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Bay-Jensen, Anne C., Platt, Adam, Siebuhr, Anne Sofie, Christiansen, Claus, Byrjalsen, Inger, Karsdal, Morten A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719735/
https://ncbi.nlm.nih.gov/pubmed/26787505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0913-x
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