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Canine Distemper Virus Fusion Activation: Critical Role of Residue E123 of CD150/SLAM

Measles virus (MeV) and canine distemper virus (CDV) possess tetrameric attachment proteins (H) and trimeric fusion proteins, which cooperate with either SLAM or nectin 4 receptors to trigger membrane fusion for cell entry. While the MeV H-SLAM cocrystal structure revealed the binding interface, two...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Khosravi, Mojtaba, Bringolf, Fanny, Röthlisberger, Silvan, Bieringer, Maria, Schneider-Schaulies, Jürgen, Zurbriggen, Andreas, Origgi, Francesco, Plattet, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719633/
https://ncbi.nlm.nih.gov/pubmed/26608324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02405-15
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