Host MicroRNA miR-197 Plays a Negative Regulatory Role in the Enterovirus 71 Infectious Cycle by Targeting the RAN Protein

Enterovirus 71 (EV71), a member of Picornaviridae, is associated with severe central nervous system complications. In this study, we identified a cellular microRNA (miRNA), miR-197, whose expression was downregulated by viral infection in a time-dependent manner. In miR-197 mimic-transfected cells,...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Tang, Wen-Fang, Huang, Ru-Ting, Chien, Kun-Yi, Huang, Jo-Yun, Lau, Kean-Seng, Jheng, Jia-Rong, Chiu, Cheng-Hsun, Wu, Tzong-Yuan, Chen, Chung-Yung, Horng, Jim-Tong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719623/
https://ncbi.nlm.nih.gov/pubmed/26581983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02143-15
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