Enhanced Immune Responses to HIV-1 Envelope Elicited by a Vaccine Regimen Consisting of Priming with Newcastle Disease Virus Expressing HIV gp160 and Boosting with gp120 and SOSIP gp140 Proteins

Newcastle disease virus (NDV) expressing HIV-1 BaL gp160 was evaluated either alone or with monomeric BaL gp120 and BaL SOSIP gp140 protein in a prime-boost combination in guinea pigs to enhance envelope (Env)-specific humoral and mucosal immune responses. We showed that a regimen consisting of an N...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Khattar, Sunil K., DeVico, Anthony L., LaBranche, Celia C., Panda, Aruna, Montefiori, David C., Samal, Siba K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719621/
https://ncbi.nlm.nih.gov/pubmed/26581986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02847-15
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