Genome-Wide Mapping of the Binding Sites and Structural Analysis of Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 2 Reveal that It Is a DNA-Binding Transcription Factor

The oncogenic herpesvirus Kaposi's sarcoma-associated herpesvirus (KSHV) is known to encode four viral interferon regulatory factors (vIRF1 to -4) to subvert the host antiviral immune response, but their detailed DNA-binding profiles as transcription factors in the host remain uncharacterized....

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hu, Haidai, Dong, Jiazhen, Liang, Deguang, Gao, Zengqiang, Bai, Lei, Sun, Rui, Hu, Hao, Zhang, Heng, Dong, Yuhui, Lan, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719618/
https://ncbi.nlm.nih.gov/pubmed/26537687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01392-15
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