Mumps Virus Nucleoprotein Enhances Phosphorylation of the Phosphoprotein by Polo-Like Kinase 1

The viral RNA-dependent RNA polymerases (vRdRps) of nonsegmented, negative-sense viruses (NNSVs) consist of the enzymatic large protein (L) and the phosphoprotein (P). P is heavily phosphorylated, and its phosphorylation plays a critical role in viral RNA synthesis. Since NNSVs do not encode kinases...

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Bibliographic Details
Published in:J Virol
Main Authors: Pickar, Adrian, Zengel, James, Xu, Pei, Li, Zhuo, He, Biao
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719615/
https://ncbi.nlm.nih.gov/pubmed/26608325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02160-15
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