Mechanism of Cell Culture Adaptation of an Enteric Calicivirus, the Porcine Sapovirus Cowden Strain

The porcine sapovirus (SaV) (PoSaV) Cowden strain is one of only a few culturable enteric caliciviruses. Compared to the wild-type (WT) PoSaV Cowden strain, tissue culture-adapted (TC) PoSaV has two conserved amino acid substitutions in the RNA-dependent RNA polymerase (RdRp) and six in the capsid p...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Lu, Zhongyan, Yokoyama, Masaru, Chen, Ning, Oka, Tomoichiro, Jung, Kwonil, Chang, Kyeong-Ok, Annamalai, Thavamathi, Wang, Qiuhong, Saif, Linda J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719606/
https://ncbi.nlm.nih.gov/pubmed/26581980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02197-15
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