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Ancestral Mutations Acquired in Refrex-1, a Restriction Factor against Feline Retroviruses, during its Cooption and Domestication

Endogenous retroviruses (ERVs) are remnants of ancestral retroviral infections of germ cells. Retroviral endogenization is an adaptation process for the host genome, and ERVs are gradually attenuated or inactivated by mutation. However, some ERVs that have been “domesticated” by their hosts eventual...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Ito, Jumpei, Baba, Takuya, Kawasaki, Junna, Nishigaki, Kazuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719600/
https://ncbi.nlm.nih.gov/pubmed/26581999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01904-15
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