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Tat protein of human immunodeficiency virus type 1 represses expression of manganese superoxide dismutase in HeLa cells.

Using a HeLa cell line stably transfected with the tat gene from human immunodeficiency virus type 1, we have found that the expression of the regulatory Tat protein suppresses the expression of cellular Mn-containing superoxide dismutase (Mn-SOD). This enzyme is one of the cell's primary defenses a...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Flores, S C, Marecki, J C, Harper, K P, Bose, S K, Nelson, S K, McCord, J M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8395050/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7632
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