Tankyrase inhibition impairs directional migration and invasion of lung cancer cells by affecting microtubule dynamics and polarity signals

BACKGROUND: Tankyrases are poly(adenosine diphosphate)-ribose polymerases that contribute to biological processes as diverse as modulation of Wnt signaling, telomere maintenance, vesicle trafficking, and microtubule-dependent spindle pole assembly during mitosis. At interphase, polarized reshaping o...

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發表在:BMC Biol
Main Authors: Lupo, Barbara, Vialard, Jorge, Sassi, Francesco, Angibaud, Patrick, Puliafito, Alberto, Pupo, Emanuela, Lanzetti, Letizia, Comoglio, Paolo M., Bertotti, Andrea, Trusolino, Livio
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719581/
https://ncbi.nlm.nih.gov/pubmed/26787475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-016-0226-9
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