Tankyrase inhibition impairs directional migration and invasion of lung cancer cells by affecting microtubule dynamics and polarity signals

BACKGROUND: Tankyrases are poly(adenosine diphosphate)-ribose polymerases that contribute to biological processes as diverse as modulation of Wnt signaling, telomere maintenance, vesicle trafficking, and microtubule-dependent spindle pole assembly during mitosis. At interphase, polarized reshaping o...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:BMC Biol
Autori principali: Lupo, Barbara, Vialard, Jorge, Sassi, Francesco, Angibaud, Patrick, Puliafito, Alberto, Pupo, Emanuela, Lanzetti, Letizia, Comoglio, Paolo M., Bertotti, Andrea, Trusolino, Livio
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719581/
https://ncbi.nlm.nih.gov/pubmed/26787475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-016-0226-9
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