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Tankyrase inhibition impairs directional migration and invasion of lung cancer cells by affecting microtubule dynamics and polarity signals
BACKGROUND: Tankyrases are poly(adenosine diphosphate)-ribose polymerases that contribute to biological processes as diverse as modulation of Wnt signaling, telomere maintenance, vesicle trafficking, and microtubule-dependent spindle pole assembly during mitosis. At interphase, polarized reshaping o...
Gorde:
Argitaratua izan da: | BMC Biol |
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Egile Nagusiak: | , , , , , , , , , |
Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
BioMed Central
2016
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4719581/ https://ncbi.nlm.nih.gov/pubmed/26787475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-016-0226-9 |
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