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Circuits of cancer drivers revealed by convergent misregulation of transcription factor targets across tumor types
BACKGROUND: Large tumor genome sequencing projects have now uncovered a few hundred genes involved in the onset of tumorigenesis, or drivers, in some two dozen malignancies. One of the main challenges emerging from this catalog of drivers is how to make sense of their heterogeneity in most cancer ty...
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| Опубликовано в: : | Genome Med |
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| Главный автор: | |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4719577/ https://ncbi.nlm.nih.gov/pubmed/26792175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0260-1 |
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