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Circuits of cancer drivers revealed by convergent misregulation of transcription factor targets across tumor types

BACKGROUND: Large tumor genome sequencing projects have now uncovered a few hundred genes involved in the onset of tumorigenesis, or drivers, in some two dozen malignancies. One of the main challenges emerging from this catalog of drivers is how to make sense of their heterogeneity in most cancer ty...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Genome Med
मुख्य लेखक: Gonzalez-Perez, Abel
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719577/
https://ncbi.nlm.nih.gov/pubmed/26792175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0260-1
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